At 16:02 UTC, Friday, May 25, 2012, the SpaceX Dragon officially became the first privately-owned commercial spacecraft to be captured by and berthed at the International Space Station. It is (if I've done the math correctly) the 114th spacecraft to dock with ISS, including the missions sent up to build the station. It is the first privately-owned commercial spacecraft in history to do so.
You can read more about this in my last post, which also has a few pictures from the approach and capture.
Congratulations to NASA and the team at SpaceX! Fantastic.