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Maniac trailer: Check out the first color-coded teaser featuring Jonah Hill and Emma Stone

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Jul 30, 2018, 11:01 AM EDT

"Once you begin to appreciate the structure of the mind, there's no reason to believe that anything about us can't be changed. The mind... can be solved." So says the narrator in the first teaser trailer for Netflix's limited series Maniac.

Based on the Norwegian series of the same name, the upcoming psychological comedy follows a pair of individuals enrolled in an enigmatic pharmaceutical trial that (naturally) begins to mess with their heads. The initial trailer, which dropped online over the weekend, is pretty simple, but goes through an ever-changing color scheme, obviously meant to highlight the different moods and states of mind our characters will be experiencing during their chemically enhanced trip. 

Directed by Cary Fukunaga of True Detective fame, the show brings the star power in the form of Jonah Hill (Owen Milgrim), Emma Stone (Annie Landsberg), Sally Field, and Justin Theroux (Dr. James K. Mantleray).

According to the official synopsis from Netflix, the show is set in a parallel universe that is "somewhat like our world, in a time quite similar to our time." With this fairy-tale description setting the stage, we meet our two main leads, Annie Landsberg (Stone) and Owen Milgrim (Hill). Annie, "disaffected and aimless," is stuck on the fractured relationships she shares with her mother and sister.

Owen, on the other hand, comes from a family of rich New York industrialists and may or may not have schizophrenia. However, both individuals will get the chance at a fresh start when they join a radical, three-day drug trial run by Dr. Mantleray (Theroux). He's a confident medical practitioner who claims he can fix any issue of the mind, be it mental illness or heartbreak. His voice is presumably the one you hear in the teaser.

Gathered with 10 other strangers at Neberdine Pharmaceutical and Biotech, Annie and Owen are told that the drugs they are to ingest will have no side effects and "solve all their problems, permanently. Things do not go as planned."

Based on this description, the show sounds like a combination of Legion, Shutter Island, Limitless, and When Harry Met Sally

Maniac gets committed into Netflix Sept. 21.