WARNING! The following may contain plot spoilers for Venom!
Written by Sean Ryan and drawn by Szymon Kudranski, the comic follows Eddie Brock (played by Tom Hardy in the movie) after he's already moved to San Francisco from New York City. He's approached in Mrs. Chen's bodega by Dora Skirth (Jenny Slate's character), who needs his help in exposing the attrocities committed by Carlton Drake (Riz Ahmed).
Eddie refuses and later grapples with an evil voice inside his head before being approached by Drake's people, who want the symbiote back. However, they don't call it a "symbiote" or even "alien substance." They refer to it as a "bug," which fits Venom's Spider-Man-influenced look. They state that once the host is dead, the "bug" will be forced out into the open, allowing them to recapture it.
Venom takes over and beats up Drake's men, so that Eddie can escape his apartment and partake in an action-filled motorcyle race through the streets of San Fran. Drake sends his drones after the fugitive and Eddie is eventually cornered by one of Drake's men. Luckily, Venom makes his first full "We Are Venom" appearance that we see in the trailers, and prepares to feed on the thug.
Throughout the chase, Eddie asks the voice if it's a parasite or a brain tumor, at which the symbiote takes great offense. "First you call me a parasite. Now you're calling me a brain tumor. On my planet, that's a good way to get yourself eaten." That planet, by the way, is Klyntar, homeworld of the symbiotes.
Now, we've seen a lot of these moments in the trailers, but it would still be weird for Sony to want to spoil an entire chunk of the plot before the movie even comes out. That's why you should probably consider this comic as more of a companion than a bona fide excerpt of the shooting script turned into a comic book. Moreover, Kudranski's art does not use the likenesses of the main cast members (Hardy, Slate, Ahmed), supposedly because it would have cost more money to pay the actors for the use of their faces. Only the Eddie on the cover (drawn by SKAN) resembles Hardy.