As you might recall, all is not well in the life of Peter Parker. His body has been hijacked by Doc Ock, and now he's stuck in the bad Doc's dying shell. Couldn't get any worse, right? WRONG.
You kids at home might not remember this, but there was a time during which Otto Octavius tried to marry Aunt May. Yes, really. And she was game for it. In fact, even though he had some ulterior motives, Otto always had a bit of a soft spot (in his own, creepy way) for Peter's aunt.
What makes that old plot point relevant is that Doc Ock inherited Peter's memories when they swapped bodies. Likewise, Peter now remembers everything from Otto's life. And, oh, dear. As Peter scours those memories to try and figure out how he's found himself in this predicament, he discovers a memory he wishes he hadn't.
To the videotape!
Yes, that's right. Otto and May, uh, apparently decided to consummate their marriage a little early. Now Peter knows it and, God help us, so do we.
(via Comic Book Movie)