WARNING: If you don't want to know what happens in this episode, don't read this photo recap!
Doc has managed to get himself separated from the group … and unwillingly admitted into the Serenity Falls Institution for the Criminally Insane, a mental asylum filled with a ragtag group of patients lorded over by Nurse Ratched (heh heh) …
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… and surrounded by zombies. How long before they get in and go crazy on the crazies?
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Nurse Ratched and her brood overheard Doc saying he was, well, a doctor (more or less), and his quick psychological analysis of all the patients is impressive enough to get him out of his restraints and accepted as a colleague.
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Nurse Ratched takes Doc to see the facility's latest and most troubling guest: 10K, who's near-catatonic from lack of the vaccine that keeps him from falling under Murphy's control.
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Nurse Ratched had scheduled a lobotomy for the new patient but Doc convinces her that he's only suffering from '10K Fever' and in need of meds. To get to the fully stocked pharmacy, Doc and Elvis must traverse the 'Z ward,' an area of the hospital overrun with zombies who turned during electroshock treatment.
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After Doc and Elvis return with the drugs from the pharmacy, Doc cooks up an impromptu cocktail that seems to at least keep 10K from getting any worse.
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Doc starts providing the patients with medication that might actually help with their various conditions.
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Elvis then brings in 10K, who's feeling 'super-mellow' but is at least somewhat coherent. 10K tells Doc of Murphy's plans to create a New World Order up in Spokane, after which they attempt to flee from the facility.
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Unfortunately, Doc and 10K's escape attempt is thwarted by Nurse Ratched and she has them put in strait jackets. After Doc tells her of their mission to take Murphy to the CDC to cultivate a cure for the Z virus, Ratched is more than convinced that they're delusional.
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Nurse Ratched prepares to lobotomize Doc, though a hulking patient named Bob comes to the rescue and kills her. The patients rise up!
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Doc manages to rally the patients and make a run for a bus that's parked outside just as the zombies break through the building's feeble barricades.
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Once everyone's outdoors, 10K collapses, prompting the patients to leave him and Doc behind as they take off in the bus.
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Doc discovers 10K's Murphy bite and despairs for his friend … and wonders whether the vials in his bag are the cure or what's making him sick. Doc swears to punch in Murphy's teeth as 10K makes him promise not to tell Roberta and the others about his condition.
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The episode ends with the patients heading for an unknown destination on board their crazy bus, running over a Z along the way. It's a mad world!